Dr. Amiri graduated with his medical degree in his home country of Iran. After finishing his residency in Surgery and Urology in Denmark, he pursued a fellowship in Kidney Transplantation there as well as Abdominal Organ Transplantation at the University of Tennessee. He has served as a tenured professor at the University of Tennessee and most recently at LSU Health Sciences Center Shreveport. He is currently the Surgical Director of Liver Transplantation at John C. McDonald Regional Transplant Center.

He has published over 160 articles in scholarly journals on hepato-pancreato-biliary diseases, and liver, pancreas, and kidney transplantation. He has reviewed the work of other distinguished physicians and surgeons. He has co-authored 13 books and book chapters and has been the editor of 2 books. Dr. Amiri has worked to establish liver transplant programs, specifically living-related liver transplants, both in the United States and abroad.

Dr. Amiri is a member of the American College of Surgeons, the Southern Surgical Society, and both the American Society of Transplant Physicians and the American Society of Transplant Surgeons. He is also a member of the Americas Hepato-Pancreato-Biliary Association, International Hepato-Pancreato Biliary Association, the Iranian American Medical Association, and the John C. McDonald Surgical Society among others.

Additionally, he has served as the Medical Director of Louisiana Organ Procurement Association, the President of John C. McDonald Surgical Society, and past President of The Transplant Society. Dr. Amiri is currently the President of the Louisiana Chapter of the American College of Surgeons.

He has given lectures at conferences worldwide bringing his widespread experience to the training of other surgeons and physicians. Over the course of his ongoing career, Dr. Amiri has trained numerous medical professionals throughout the world in organ transplant techniques. 

Dr. Amiri developed the porto-enteric technique for pancreas transplantation in 1990, and his technique has been used worldwide ever sense.